THE CULTURE OF WHOLE ORGANS

The Culture of Whole Organs

1. A technique has been developed for the transplantation of the whole thyroid into the Lindbergh pump, and its perfusion, without the occurrence of infection, emboli, and other complications. 2. The gland remains alive during the period of perfusion, which lasted from 3 to 21 days. 3. The technique is simple enough to be used as a routine procedure for physiological or pathological studies of ...

The Culture of Whole Organs

1. Perfusion of isolated thyroid glands from rabbits, made refractory to the action of the thyro-stimulating factor from the hypophysis by repeated injections for 2 months, has shown that in this condition the thyroid epithelium responds to pituitary stimulation. 2. The serum from refractory rabbits does not neutralize completely the thyro-stimulating effect of anterior pituitary extract upon a...

An Apparatus for the Culture of Whole Organs

An apparatus has been developed which maintains, under controllable conditions, a pulsating circulation of sterile fluid through organs for a length of time limited only by the changes in the organ and in the perfusion fluid.

The Culture of Organs

A list, with titles, of about 120 papers by the author and his colleagues is followed by a classified list of important contributions by others in the fields discussed. Author and subject indices are given. Adventures in Respiration is not a physiological monograph in the usual sense, but rather the scientific autobiography of one of America's leaders in the physiology of respiration. The layma...

The Use of Whole Animals Versus Isolated Organs or Cell Culture in Research